Midazolam Enhances Mutant Huntingtin Protein Accumulation via Impairment of Autophagic Degradation In Vitro

Background/Aims: Autophagy is a well-known pathway to “clean” the misfolded mutant huntingtin protein (mHtt), which plays a considerable role in polyglutamine diseases. To date, there have been few studies of the choice of anesthetic during surgery in patients with polyglutamine diseases and evaluat...

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Main Authors: Jiqian Zhang (Údar), Wei Dai (Údar), Pengcheng Geng (Údar), Li Zhang (Údar), Qilian Tan (Údar), Dan Cheng (Údar), Pengfei Wei (Údar), Zhilai Yang (Údar), Lei Zhang (Údar), Erwei Gu (Údar), Guanghong Xu (Údar), Chaozhao Liang (Údar), Xuesheng Liu (Údar)
Formáid: article
Foilsithe: Karger Publishers, 2018-07-01T00:00:00Z.
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