A new method for the reproducible generation fo polymorfs: two forms of sulindac with very different solubilities

Polymorphism of drugs has been the subject of intense interest in the pharmaceutical industry for over forty years. Although identical in chemical composition, polymorphs differ in bioavailability, solubility, dissolution rate, chemical and physical stability, melting point, colour, filterability, d...

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Principais autores: Llinás, Antonio (Autor), Box, Karl J (Autor), Burley, Jonathan C (Autor), Glen, Robert (Autor), Goodman, Jonathan (Autor)
Formato: IRs
Publicado em: International Union of Chrystallography, 2008-01-10T15:12:42Z.
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